When Jessica Lowe was a little girl in The Bahamas, she never imagined she would one day lead stroke codes in red lipstick or stand at the center of a campaign that raised over $88,000 for women’s heart health. But then again, Jessica, now known to the world as Doctor Brain Barbie, has never been one to follow the script. Her journey from island roots to double-boarded neurologist and epileptologist, medical educator, advocate, and digital creator is a story of intellect and courage, but also of style, humor, and heart.
The white coat is often imagined as a uniform stripped of personality, where seriousness is valued above all else and where doctors are expected to mute themselves to fit a mold. Jessica decided early on that she would not dilute who she was to fit in. She shows up to her work in pink scrubs or heels, blending glamour with expertise, and insists on being fully herself while doing some of the most complex work in medicine. “You can save lives in stilettos and still know your EEG from your MRI,” she often says with a laugh, and that truth has shaped the brand she created, Doctor Brain Barbie.
Her brand was born not as a marketing ploy, but as a mission. Too often, Jessica noticed patients leaving their appointments confused, overwhelmed, or unheard. Women in particular struggled to have their symptoms taken seriously. She saw gaps in how neurology was explained and how inaccessible the information felt to everyday people. Doctor Brain Barbie became her answer: a platform that translated intimidating science into clear, relatable lessons wrapped in creativity and confidence. The goal was simple: to make brain health approachable while demonstrating that brilliance and femininity can coexist and thrive together.
Jessica’s career has been marked by persistence in the face of stereotypes. She has been mistaken for a nurse after introducing herself as a doctor, and she has had to prove her knowledge again and again in rooms where appearance was used as a reason to underestimate her. Instead of backing down, she leaned into her difference, choosing to let her competence and her voice speak louder than prejudice. When she once walked into a stroke code in stilettos, the room fell silent until she gave the next direction in the treatment algorithm. The pause quickly turned to action, and Jessica was reminded that presence and leadership often come from certainty and skill, not conformity.
What makes Doctor Brain Barbie stand apart is the way Jessica blends medicine with culture and storytelling. She is not just sharing facts about seizures or migraines. She is creating viral trends like the “McMigraine” series that caught fire across TikTok, helping thousands of people recognize symptoms, seek care, and feel seen. She is bringing humor into discussions about neurology without losing credibility, and that combination has made her a trusted and relatable figure. One follower even wrote to her saying that, because of her videos, she realized her symptoms were seizures and was able to get proper treatment. Those messages fuel Jessica’s drive, reminding her that advocacy online is not about likes, it is about saving lives.
Her influence extends far beyond social media. She serves on the board of the Epilepsy Foundation of Delaware, and her leadership on the executive committee for the American Heart Association’s Go Red for Women campaign earned her the 2025 Woman of Impact title. Her team’s fundraising efforts were not just numbers on a screen; they represented lives touched, awareness raised, and a movement carried forward. Jessica dedicated the campaign to a young woman named Noelle Hunter, a heart survivor whose strength and resilience inspired her. For Jessica, that campaign was a deeply personal reminder that behind every title, every recognition, and every statistic, there are real people and real stories.
Doctor Brain Barbie is more than a catchy name. It is a declaration that you do not have to strip yourself of personality, style, or identity to be taken seriously in medicine. Jessica embraces the parts of herself that the field has traditionally told women to hide. She is bold, fashionable, and outspoken, but also precise, analytical, and deeply committed to science. By doing so, she has created space for others to show up fully too, mentoring young women in medicine and encouraging them not to shrink themselves to fit outdated norms.
Her achievements are impressive: leading hospital epilepsy programs, earning recognition on MSN’s “Top 10 Health Experts Transforming Wellness in 2025,” and building a digital platform with a global reach. But perhaps what matters most is her vision for the future. Jessica dreams of creating a global movement where brain health is not just understood but celebrated. She envisions hosting a health-focused television series, speaking on the world’s biggest stages, and building patient education tools that are as engaging as they are informative. She also hopes to inspire a generation of “Field Barbies” – women across every discipline who demonstrate that excellence and individuality can walk hand in hand.
Jessica Lowe, Doctor Brain Barbie, is not trying to blend in. She is intentionally standing out because she knows that visibility matters. Representation matters. And the next generation of women in medicine needs to see that leadership can wear heels, drive fast cars, and still carry the weight of expertise that changes lives.
Her story is proof that intelligence and glamour are not opposites but allies. Her mission is to make medicine more human, more authentic, and more unapologetically bold. In every patient she treats, every video she shares, and every barrier she breaks, Jessica is reshaping what it means to be both doctor and woman and inspiring others to believe that they, too, can own every part of who they are.
Follow her on Instagram and TikTok at @doctorbrainbarbie to see how she continues to blend knowledge with confidence and make brain health accessible to all.
